The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the nation’s medical research agency — making important discoveries that improve health and save lives.
The broad goal of the Investigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project grant is to encourage research that focuses on the development, characterization, or improvement of animal models and related biological materials for Down syndrome (DS) research. This includes enhancing access to information about or from the use of these animal models. The grant supports projects that have utility in targeted or basic science studies highly relevant to Down syndrome. Projects can focus on a variety of areas such as the development of different animal models, genetic resources, single cell or subcellular level atlases, advanced informatics technologies (including artificial intelligence and machine learning), and the integration of multiple animal models and technology platforms to increase the rigor and reproducibility of preclinical Down syndrome research.