The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the nation’s medical research agency — making important discoveries that improve health and save lives.
This grant program, through the NHLBI-funded TransOmics for Precision Medicine (TOPMed), aims to generate an expansive volume of integrated genetic and multi-omics data to unveil the molecular mechanisms underlying heart, lung, blood, and sleep (HLBS) disorders. The program's broad goal is to evolve from merely mapping genetics to understanding mechanisms (M2), addressing knowledge gaps in the TOPMed datasets. No direct funding is provided under this FOA, but the generated omics and phenotypic data will be shared in NIH-designated controlled-access databases such as dbGaP and NHLBIs BioData Catalyst.