Omics Phenotypes Related to Down Syndrome for the INCLUDE Project (X01 Clinical Trial Not Allowed)

From US Department of Health & Human Services: National Institutes of Health (NIH)

The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the nation’s medical research agency — making important discoveries that improve health and save lives.

Type of Support

Overview

This grant aims to harness the NIH INCLUDE Project's resources to generate extensive genomic and multi-omics data, aiming to unlock the molecular mechanisms underlying health conditions associated with Down syndrome. The initiative encourages applicants to conduct omics analyses on existing biospecimens from individuals with Down syndrome and control groups. Specifically, the grant supports whole genome sequencing, exome sequencing, epigenome mapping, and transcriptome sequencing among other omics strategies. An additional focus is on enhancing racial and ethnic diversity within study cohorts. All resulting data and associated clinical information will be integrated into the INCLUDE Project's controlled-access database, although direct funding to applicants is not provided under this opportunity.

Eligibility

Organization's Location
ea quis
Program Location
ea
Organization Type
not specified

Submission

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