The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the nation’s medical research agency — making important discoveries that improve health and save lives.
The grant focuses on addressing the gaps in knowledge regarding the biologic mechanisms of age-related diffuse white matter disease and its vascular contributions to cognitive impairment and dementia. This includes studying the cellular, molecular, tissue, and brain circuit level aspects to understand the disease's etiology, regional vulnerability, and progression over time. The ultimate goal is to inform future efforts aimed at reducing the illness burden due to vascular contributions to cognitive impairment and dementia.