The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the nation’s medical research agency — making important discoveries that improve health and save lives.
This grant program aims to enhance the understanding of the vascular pathophysiology related to Alzheimer’s Disease-Related Dementia (ADRD) by promoting the development and dissemination of innovative tools, technologies, methods, and materials. It focuses specifically on advancing combined neuropathology and neuroimaging research to elucidate the mechanisms behind Amyloid Related Imaging Abnormalities (ARIA) induced by anti-Aβ monoclonal antibody treatment. The initiative encourages the creation of resources to aid the research community in conducting studies that integrate neuropathological insights with clinical neuroimaging findings, thereby improving the comprehension of ARIA's vascular origins and pathophysiological implications. A unique aspect of this funding opportunity is the requirement of a Plan for Enhancing Diverse Perspectives (PEDP) in the application, highlighting the program's commitment to incorporating diverse scientific viewpoints. The grant provides up to $1.0M in direct costs annually for projects, with a maximum duration of five years, contingent on the scope and needs of the proposed research.